Using Hot Peppers As An Appetite Suppressant

The active heat source in all hot peppers is the potent compound capsacin. It is also the active compound that makes pepper spray such an effective weapon. If you enjoy torturing your tongue you can try the jalapeno or habenero. Another case altogether is the Bhut Jolokia. It has been certified as the world’s hottest pepper by the Guinness Book of World Records. Just in case oral torture is not your thing, there are the many-fold health benefits of the hot pepper to consider. Either way, hot peppers should be part of your healthy diet and lifestyle.

For many centuries people have used hot peppers as powerful medicinal aids. They are used to stimulate digestion, reduce appetite, increase circulation, pain relief, suppress the common cold, and to open clogged airways in the nose and lungs. That is not a bad set of benefits, but it is just the start. The health benefits continue on to include lowering cholesterol, reducing blood clotting and treating the symptoms of chronic fatigue, asthma, and infections.

Some of the most incredible benefits of hot peppers is for reducing appetite. The type of hot pepper may not matter, although some people claim that red (cayenne) peppers work the best. The capsacin is actually the relevant compound for reducing your appetite with hot peppers. Capsacin increases blood flow to the intestines and increases the muscular contractions of the intestinal walls (peristalsis). It also seems to block the sensory information from the intestine to the brain.

Therefore, it blocks hunger signals from reaching your brain. You will not even know that you are hungry. Eating less will lead to weighing less. One other way that hot peppers help you lose weight is that they can speed up your metabolism. That is three of the big hitters in weight loss: low appetite, decreased calorie intake, and increased metabolism. All from one compound. It seems that capsacin can do many things.

There are probably one to two hundred different hot pepper diets on the web right now. There are a half of a dozen methods of delivering the capsacin into your body. They all are just different ways of doing the same thing. They promote the use of the capsacin in hot peppers for reducing appetite, relieving pain, or increasing circulation. This compound can help you lose weight, heal wounds through increased circulation, and make you feel better by relieving pain.

Using hot peppers for reducing appetite has been a well known herbal treatment in Asia for centuries. Different sources give varying information as to how it works. Some believe that the capsacin they contain blocks messages between the intestines and brain, others think that capsacin simply makes you feel full. Which ever is the cause, the benefits of hot peppers in weight loss are indisputable. The type of pepper is not extremely important, but cayenne, or red, peppers are the most commonly used. You have to be careful though. The usual side effects are burning and upset stomach. It is best if you start with low doses and increase them until you have reached the optimal amount for your health. Whether you want to use hot peppers for appetite suppression, metabolic increase, or weight loss their benefits have been proven over the centuries.

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GHRP-2

GHRP-2

CAS:
Formula: C45H55N9O6
Molecular weight: 817.9
Peptide purity: > 98.0%
Appearance: White powder
Related substance: Total Impurities(%) = 2.0%
Acetate content: = 15.0%
Bacterial Endotoxins: =5 IU/mg
Chain:D-Ala-D-ß-Nal-Ala-Trp-D-Phe-Lys-NH2

Uses

Improve sex drive and desire by stimulation of hypothalamus
Reduces belly fat through lipolysis
Increases energy and vitality
Improves skin elasticity, ridding wrinkles
Increases endurance
Accelerates healing from wounds or surgery
Strengthens the heart
Enhances the immune system
Increases IGF-1 production, by as much as 50% in first week
Improves sleep quality
Increases calcium retention, strengthens and increases the mineralization of bone, bone density
Increases protein synthesis,
Improves eyesight and vision
Reduces liver uptake of glucose, an effect that opposes that of insulin
Promotes liver glucogenesis
Contributes to maintenance and function of pancreatic islets

GHRP2 growth hormone releasing peptide therapy is considered one of a few medical means of reversing the effects of aging in adults deficient in growth hormone. This is because of the benefits resulting from the increased stimulation and secretion of human growth hormone by the pituitary gland hypothalamus,axis HPA.

GHRP-2 also known as KP 102 is a commercially synthesized, growth hormone releasing hexapeptide. It is a super-analog of the GHRP-6 which is capable of potent stimulatory effect on growth hormone (GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol).

Growth Hormone Releasing Peptide 2(GHRP-2) substantially stimulates the pituitary gland’s increased natural production of the body’s own endogenous human growth hormone (hgH). This therapy consists of daily periodic sub-lingual dosing. Growth Hormone releasing peptide 2, GHRP-2 has shown on it’s own to robustly increase IGF-1 levels, and even greater results occurred when used with Growth Hormone Releasing Hormone (GHRH) to which also stimulates the pituitary gland to produce increased natural secretion of human growth hormone. This also boosts the hypothalamus function as well.

GHRP-2 is a true hgH secretagogue. It stimulates the body’s own secretion of hgH as explained herein. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat). GHRP2 has demonstrated that it is very effective at stimulating GH production in research test subjects. It has a short half life with peak concentrations occurring around 15 minutes and not longer than 60 minutes after administration.

Growth hormone releasing peptide is a commercially synthesized, non-natural super-analog of the GHRP-6 which is capable of potent stimulatory effect on growth hormone (GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol (Arvat et al. 1997). It is also a synthetic agonist of ghreline that is binding with the growth hormone (GH) secretagogue receptor. GHRP-2 has been shown to affect and induce growth hormone secretion. The response of natural physiologic system includes increase in levels of calcium ion influx alongside with increased release of growth hormones in response to this peptide (Wu et al. 1994). Its chemical structure and other chemical properties are described below:

Furthermore, dose-dependent investigations have proven that this analog is similar in terms of potency with GRF and was even tenfold more potent than earlier generations of GH-releasing secretors such as GHRP-6 and GHRP-1 (Wu et al. 1994). Because of such effects, this hormone has been used for the treatment of different monkey deficiencies and catabolic states. Studies of Laferre et al. (2005) have shown that GHRP-2 acts like ghrelin which induces food intake in monkeys and also stimulates GH secretion. This has been demonstrated when GH levels rose significantly during GHRP-2 infusion (AUC 5550 ± 1090 µg/L/240 min vs. 412 ± 161 µg/L/240 min, p = 0.003). Also, GHRP-2 has shown to be inducing secretion of cAMP in cells in a manner similar to that of GRF. GHRP-2 supplication has also acted as an anti-inflammatory effect in arthritic rats and seems to be mediated by ghrelin receptors directly on immune cells (Granado et al. 2004). However, it is important to note that the level of results with the action of GHRP-2 differs accordingly with species specifically in the response of the pituitary somatotrophs probably because of differences in the subtypes of GHRP receptors (Wu et al. 1996). Its action however in the physiologic system is blocked by GRF receptor antagonist which acts through a different receptor to that employed by earlier GHRPs.

Arnold Schwarzenegger’s Old School Bodybuilding Workout

Arnold Schwarzenegger’s Old School Bodybuilding Workout

Arnold is probably the most famous bodybuilder of all time, he won Mr. Olympia
seven times (1970-1975, 1980) and brought bodybuilding into the national spotlight
in the movie “Pumpin Iron”.

Arnold’s Top Form Measurements

Arms 22 inches
Chest 57 inches
Waist 34 inches
Thighes 28.5 inches
Calves 20 inches
Weight 235 pounds
Height 6’2″

Arnold was from the old “No Pain No Gain” school of bodybuilding and his
routines consisted of high sets and reps, mostly not to failure. He trained
each muscle group three times each week (except calves, forearms & abs
which he trained every day), using a six day split routine.

There was very little rest between sets, and he usually increased weight each
and every set. Although he experimented with high reps at times, he usually
preferred a rep range of about 6 to 10.

The following is a typical Arnold routine, but be aware that Arnold’s routine
changed constantly. At times he trained twice a day, while at other times
once a day was enough. There were periods when he did lots supersets
and giant sets. Arnold tried every thing, and picked what worked best for
him at that particular time. By mixing things up he challenged his strength
and endurance and the training variety helped keep him fresh and motivated!

Remember this is a very advanced bodybuilding routine and should not be used
by beginners or intermediates, and even advanced bodybuilder’s should only
take what they think will work best for them and adapt it to their own
bodybuilding philosophy.

Arnold’s Workout Routine

Mon, Wed, Fri

Chest:
Bench press 5 x 6-10
Flat bench flyes 5 x 6-10
Incline bench press 6 x 6-10
Cable crossovers 6 x 10-12
Dips (body weight) 5 x failure
Dumbell pullovers 5 x 10-12.

Back:
Wide-grip chins (to front) 6 x failure
T-bar rows 5 x 6-10
Seated pulley rows 6 x 6-10
One-arm dumbell rows 5 x 6-10
Straight-leg deadlifts 6 x 15

Legs:
Squats 6 x 8-12
Leg press 6 x 8-12
Leg extensions 6 x 12-15
Leg curls 6 x 10-12
Barbell lunges 5 x 15

Calves:
Standing calf raises 10 x 10
Seated calf raises 8 x 15
Oneplegged calf raises (holding dumbells) 6×12

Forearms:
Wrist curls (forearms on knees) – 4 sets, 10 reps
Reverse barbell curls – 4 sets, 8 reps
Wright roller machine – to failure

Abs:
1/2 hour of a variety of nonspecific abdominal exercises, done virtually nonstop.

Tues, Thurs, Sat

Biceps:
Barbell curls 6 x 6-10
Seated dumbell curls 6 x 6-10
Dumbell concentration curls 6 x 6-10

Triceps:
Close-grip bench presses 6 x 6-10
Pushdowns 6 x 6-10
French press (barbell) 6 x 6-10
One-arm triceps extensions (dumbell) 6 x 6-10

Shoulders:
Seated barbell presses 6 x 6-10
Lateral raises (standing) 6 x 6-10
Rear-delt lateral raises 5 x 6-10
Cable lateral raises 5 x 10-12

Calves , Forearms & Abs:
Same as Monday, Wednesday, Friday workout

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Arnold Schwarzenegger training full body split

Heavy movements stimulate the deep-lying muscle fibers that lighter movements never reach. The objective is to use fewer exercises, employ heavier weights and train your whole body in one workout. I gained most of my weight and massiveness on a program of 10 exercises that I performed three times a week. After I reached a satisfactory bodyweight, I changed over to the more advanced split system and began training six days a week.”

“If you need to put on 20 pounds or more, the following program is for you.”

Gain-Weight Routine

Books by Arnold

Squats 5 x 8,8,6,6,6

Bench Presses 5 x 8,8,6,6,6

Incline Presses 5 x 8,8,6,6,6

Wide-Grip Chins 5 x 8-10

Bent-Over Rows 5 x 8,8,6,6,6

Behind-the-Neck-Presses 5 x 8,8,6,6,6

Barbell Curls 5 x 8,8,6,6,6

Lying Triceps Extensions 5 x 8,8,6,6,6

Deadlifts 5 x 3-5 (building up to one max set)

Machine Calf Raises 5 x 10-15

“The above program will build tremendous size and power, but it’s too rugged for the beginning bodybuilder. Here’s a more appropriate version for the novice.”

Beginner Routine

Bent-knee Situps 1 x 15-25
Squats 3 x 10
Bench Presses 3 x 8-10
Bent-Over Rows 3 x 8-10
Military Presses 3 x 8-10
Barbell Curls 3 x 8-10
Deadlifts 2 x 10
Machine Calf Raises 3 x 15-20
Bent-leg Leg Raises 1 x 15-25

“During the first week of training do only one set of each exercise and rest for two to three minutes between exercises. Do two sets for the second week and increase to three sets for the fourth week. If the reps are easy when you hit the top number in the listed range, add weight to the bar – five to 10 pounds is sufficient. Increase the weight whenever possible, but use correct form at all times without straining. Beginners can make continuous progress for at least three months on this program.”

“If you’re a bodybuilder who works long hours or has limited time to train for some other reason, try the following routine.”

Abbreviated Mass Routine
Squats 5 x 6-8

Bench Presses 5 x 6-8
Wide-Grip Chins
or Pulldowns 5 x 8-10
Behind-the-Neck-Presses 5 x 6-8
Barbell Curls 5 x 6-8
Lying Triceps Extensions 5 x 6-8
Deadlifts 5 x 3-5 (building up to one max set)

“Although this version is somewhat shorter, some people gain faster on fewer exercises – probably because they’re able to recuperate better and they don’t become exhausted from their training.”

- “Rest for two minutes between sets of squats and deadlifts, but for most other exercises keep your rest to no more than 1 1/2 minutes.”

- “Use these programs three days a week with at least a day of rest between workouts. For example, train on Monday, Wednesday and Friday.”

Of course there was more to the article than that, but that sums it up.

What We Know About Successful Bodybuilders

 

The following statements are true for nearly every successful bodybuilder I’ve ever met.

They are consistent.
Every successful bodybuilder I’ve ever met has been training for an extended period of time. They have
remained consistent for 5, 10, 15 and even 20 years. They rarely miss workouts, or scheduled meals for that matter.

They are strong.
While most of these bodybuilders will tell you, I don’t train for strength, they are inhumanly strong. Pound for pound, most of them give me a run for the money in the strength department. I have never met a weak, successful bodybuilder.

They evolve their training.
Each of these athletes has a very distinctive form of training that suits them, and only them. They have meticulously evolved their training over the years to fit their specific needs and weaknesses.

They embrace the hard
exercises
.
One of the questions I ask most top bodybuilders is, what are your top 3 exercises for mass? 90% of them respond with squats, deadlifts and the bench press. Some prefer front squats over squats, and many prefer incline bench presses over bench presses. Each of these lifts is hard, and is certainly not avoided.

They don’t guess.
When it comes to meal plans, top bodybuilders don’t guess. You don’t hear them say “I think I am eating X amount of calories or Y grams of protein.” They know exactly what goes into their bodies.

They supplement heavily.
I know this sounds like a sales pitch, but it’s the truth. I swear I’m not trying to sell you a thing. While each of these athletes will be the first to tell you that food supplements aren’t magic pills and powders, at least 95% of the bodybuilders I’ve met use 4-10 different supplements a day, or more.

Someone is likely to call BS on this, but I assure you it’s a reality. These guys take every small advantage they can get. If you don’t believe me, go ask a top natural pro yourself.

They eat frequently.
Yes, they eat frequently. I understand that as of late intermittent fasting has become an extremely popular option in the muscle building world. I’m certainly not trying to bash the fasting community by revealing the truth about how these guys eat. It is what it is.

99% of the successful bodybuilders I’ve met eat 5, 6, 7 or 8 times a day. The only bodybuilder I’ve personally met who doesn’t eat this often is Layne Norton. I believe he eats 3-4 times a day.

They are gray.

Gray? Yes, gray. Nearly every top bodybuilder knows that there are few black and white answers in the world of muscle building and nutrition. What works for one guy might not work for another. They understand that most questions have gray answers, not black or white solutions.

 

 

Anabolic Cooking by Dave Ruel

Anabolic Cooking by Dave Ruel

Anabolic Cooking by Dave Ruel is great for people who demand that their food tastes good AND is bodybuilding-healthy at the same time. As you all know from my videos, my kitchen-skills are extremely limited so this book with all of its tasty, high protein, healthy fitness meals is a great compliment to my website. When I do my “Healthy Meals” videos, I get lots of comments about them being so boring and gross that people could never eat them. For these people, the $47 for this book is money well spent because with these easy, flavorful bodybuilding recipes at your fingertips you will be far more likely to eat strict, healthy nutritional food all the time. On the other hand, if you are someone like myself who is happy eating beans with salsa five times a day then don’t waste your money on this book because you wont end up using the recipes. Nutrition is 75% of success in bodybuilding and by having an book like this makes it more likely that your nutritional house will remain in order. All successful bodybuilders know that you cant get stronger and gain muscle mass without strict, proper nutrition and these recipes make it much easier to achieve proper nutrition. So now, you have NO more excuses not to have flawless nutrition and maximize your bodybuilding gains. If you demand tasty, flavorful food then you can buy this book and follow its excellent recipes. If you have no time or patience for cooking and are happy with simple foods and flavors then you can follow my free recipes. A solution for everyone!

You can tell that Dave Ruel (the author) knows his nutritional stuff, you wont find a bag of enriched, bleached flour or a bag of granulated sugar in HIS kitchen! Anabolic Cooking is very well written and organized with sections for breakfast, chicken and poultry, beef, fish and seafood, salads soups and sides, and snacks & bars. Its funny, Dave shies away from calling this a cookbook but that’s what it is – A cookbook for bodybuilders. Each recipe has a bubble telling you the nutritional content of the meal, you will need to adjust the quantities to give you the desired meal size.

Dave is also the author od another pretty great book – 10 Quick & Easy FAT TORCHING RECIPES 

Metabolic Cooking

1. Apple Oatmeal Pancakes ………………………………………………………Page 4
2. Ginger Beef ………………………………………………………………………..Page 5
3. Asian Turkey Burgers ……………………………………………………………Page 6
4. Hot Paprika Shrimp ……………………………………………………………..Page 7
5. Apple Mustard Pork Tenderloin …………………………………………….Page 8
6. Quinoa Burritos …………………………………………………………………..Page 9
7. Kale Chips …………………………………………………………………………Page 10
8. Cajun Style Sweet Potatoes …………………………………………………Page 11
9. Southwestern Eggs …………………………………………………………….Page 12
10. The Thermoccino Smoothie ………………………………………………..Page 13

 

Dave Ruel is the most respected and trusted fitness cook in North America and is a firm believer that eating healthy to support your body goals does not have to be plain and boring. He’s seen fitness enthusiasts go the usual route of steamed chicken, baked potatoes, and broccoli for every meal and has had the opportunity to teach them that there is a ‘better way’. With Dave’s approach, you’re never dieting – you’re just eating healthy because you love it. Dave has a large background in helping others achieve their goals, be it fat loss or muscle building and is always learning new and innovative techniques  to use in the kitchen

Beginner’s Guide To IGF1-lr3

Beginner’s Guide To IGF1-lr3

  • IGF-1 Reconstitution
  • Making 0.6% Acetic Acid from Vinegar
  • Injection Technique
  • Sterile Procedure
  • Items You Will Need
  • …and more!

Preface
The goal of this guide is to help both those that have not used IGF-1lr3 before and for those that simply would like a methodical approach to the “mechanics” of running it.  This guide does not expand on the biochemistry of IGF-1, aside from a very simple introduction to it.  I suggest reading a book or searching forums to educate yourself about the biochemistry of “peptides” or “IGF” if you require in-depth knowledge.

I am not a physician, thus cannot and do not diagnose ailments or diseases and/or nor do I suggest that IGF-1 is a remedy for any illness or diseases.  IGF-1 should be treated with much respect.  It is research compound, thus you should use at your own risk.

Currently (05/31/2008), in the United States, IGF-1lr3 is a research compound.  It is legal to own this substance to the best of my knowledge (at current time).  I am not an attorney, so please review your local law(s) regarding possession and administration of this therapeutic protein.

I do not condone the usage of IGF-1lr3 unless you are qualified to do so.  This guide is provided as a research & development tool only.

IGF-1lr3 Overivew

Background:
Long Arg3 Insulin-like Growth Factor-I (Long-R3-IGF-I) is an 83 amino acid analog of IGF-I comprising the complete IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus. Long-R3-IGF-I is significantly more potent than IGF-I in vitro. The enhanced potency is due to the markedly decreased binding of Long-R3-IGF-I to IGF binding proteins which normally inhibit the biological actions of IGFs.

Description:
Recombinant Human Long-R3-IGF-I produced in E. coli is a single, non-glycosylated, polypeptide chain containing 83 amino acids and having a molecular mass of 9111 Dalton.

0.6% Acetic Acid Overview
Acetic Acid (AA) will be used to reconstitute (turn your lyophilized IGF-1 into a liquid form) your IGF-1.  The standard is to use 0.6% AA.  This concentration is typically not available for you to purchase.  You can make your own 0.6% AA and I will show you  how below (many have used this method successfully).

Making 0.6% Acetic Acid
You will have to purchase a few items upfront.  Here is a “grocery list” of items you will need.  I have provided check boxes for you to check off once you have purchased these items.

Items Needed:
• Distilled white vinegar (grocery store)
• Distilled water (grocery store)
• 0.2-0.22um sterile Whatman syringe filter
• 10mL syringe with a luer lock tip
• ~20-22 gauge needles (just the needles)
• Sterile glass vial (10-20mL)
• Alcohol prep pads – sterile kind (70% isopropyl alcohol)




Quick Guide:
1. Swab the top of your sterile vial with alcohol prep pad (70% isopropyl alcohol)
2. Mix 7.5mL distilled water with 1.0mL vinegar
3. Add Whatman syringe filter
4. Add sterile ~20ga. needle to end of  Whatman filter
5. Inject the 8.5mL of solution into the sterile vial
6. You now have sterile 0.6% acetic acid

Detailed Directions:
1. Wash you hands thoroughly
2. Optional: wear alcohol treated exam gloves (rub your gloved hands together with 70% isopropyl alcohol on them until dry)
3. Using a sterile alcohol prep pad, swab the top of your sterile glass vial (into which the acetic acid solution will be held in)
4. Using  the 10mL syringe with a ~20ga. needle on the end, draw up 7.5mL distilled water
5. Using the same syringe, now draw up 1mL vinegar
6. Remove needle from the syringe and discard
7. Attach 0.2-0.22um Whatman sterile syringe filter (do not touch the free end that will have a needle on it)
8. Put a new, sterile needle (~20 gauge) onto the free end of the Whatman filter (do not touch needle)
a. Do not use the same needle on the Whatman that was used to originally draw up the unsterile vinegar and distilled water.
9. Put a ~20 gauge sterile needle into the top of your sterile glass vial to act as a vent
10. Inject the acetic acid solution into the vial
11. You are now done and should have sterile 0.6% acetic acid

Notes:
1. These items MUST be sterile:  20-22ga. Needles, whatman filter, glass vial
2. Whatman filter:  These small, sterile filters are used to filter the acetic acid solution so it is sterile.  It does not matter that the liquid in your syringe (distilled water & vinegar) is not sterile, nor does it matter that the syringe itself is not sterile.  Once the liquid goes through the filter it is STERILE.  Thus, everything after the filter must be sterile!
3. You will most likely use 1mL (milliliter) of 0.6% AA to reconstitute your IGF-1.  Thus, you should make at least 1.5mL.  In reality, it’s just as easy to make 8.5mL as I have stated in the above directions.  You will have plenty for use later then.
4. Do NOT reuse the Whatman filter nor any needles!  Discard immediately.

Reconstituting IGF-1lr3
Reconstitution is simply the addition of the 0.6% AA to your lyophilized IGF-1.
Assumption:  1mg/mL IGF-1/AA (1mg IGF-1 will be combined with 1mL AA; 1mg IGF-1 is the same as 1,000mcg)

1. Swab the top of your IGF-1 vial with a sterile alcohol prep pad
2. Swab the top of your 0.6% AA vial with a sterile alcohol prep pad
3. Using either multiple insulin syringe volumes (example: 2 x 0.5cc) or a single large syringe, obtain 1.0mL of 0.6% AA.
4. In the IGF-1 vial, insert a sterile ~20 ga. needle to act as a vent
5. Inject the 1.0mL of AA very slowly and dribble it down the side of the vial.
a. Be very careful with this peptide as it is very delicate!
6. Remove the needle & syringe and discard
7. Gently swirl the vial or roll between your hands.
a. Again, be very gentle here
8. You now have 1mg/mL of IGF-1
a. This is the same as:  1,000mcg/mL

Notes:
1. If you added 2mL of AA, it would be a 0.5mg/mL

Injecting IGF-1lr3
If this is your first time with injections, don’t worry.  You will be using a very fine gauge insulin syringe which means you will most likely have nearly effortless injections.  These things are so tiny and sharp you may not even feel it penetrating.  If you use sterile procedure, aspirate prior to injection, and have diluted your IGF-1/AA solution with enough bacteriostatic water (BW), you should have no issues with your injections and very minimal post-injection discomfort (if any at all!).

I cannot stress enough the importance on two topics:  A)  sterility, and B) pre-injection aspiration.  Always swab the injection site(s) with a sterile isopropyl alcohol (IPA) pad and aspirate prior to injecting the IGF-1.  No questions asked!

You will most likely intramuscular (IM) injections, but subcutaneous (sub-q) injections are also followed by some, but current theory is that IM will yield a localized effect.  By “localized effect”, I am referring to the effect IGF-1 will have at the injection site.  So if you inject IM into biceps, it is thought that your bicep muscles will get more of a dose of IGF-1 than other parts of your body (some which you don’t want to be effected, such as the intestines).  Both types of injections will have systemic effects (affecting the body as a whole).  Long R3 IGF-1 has an estimated half-life of 20-30hrs (taken from IGTROPIN data).

This guide assumes you will be doing bilateral IM injections. More below.

Bilateral injections are injections that are evenly divided between two muscles.  If you are injecting 40mcg (micrograms) bilaterally, you will be injecting 20mcg into the right bicep and 20mcg into the left bicep.

Current theorized best practice is to you inject your peptide post workout (PWO).  You have a small window of optimal opportunity.  Ideally, you would inject immediately PWO, but some do not like the idea of injecting in a public location, such as the gym.  Your next best option is to make your way home ASAP and have your needles loaded and ready (with your alcohol swabs sitting near by).

Sterility
Without a doubt, sterility is a major concern with injections.  You have to be conscious of bacteria and other infectious agents at all times when performing injections or other procedures that require sterility (such as reconstitutions and making 0.6% AA).

Bacteria (and viruses, and spores, etc) are invisible to the naked eye.  Yet they are everywhere. It is very important that you acquire sterile alcohol prep pads (make sure it says “sterile” before you buy them).  They are extremely cheap and effective.

Wash your hands! Before attempting anything requiring sterile technique, wash your hands and dry them with a clean paper towel (not the dirty towel hanging in the bathroom!).  For optimal sterility, you may purchase exam gloves (latex or non-latex) and, after putting them on, you can dump some isopropyl alcohol (IPA) onto them and rub your hands together thoroughly.  Now you really have sterile hands.  Exam gloves are very inexpensive as is the bottle of IPA.  IPA can be purchased for ~$1/bottle in the grocery store where the band-aids and whatnot.

I recommend you use a fresh syringe for each injection.
  Yes, some choose to use one syringe, but my feeling is that the syringes are so inexpensive and the risk of cross-contamination from one injection site to the other isn’t worth the risk.  Furthermore, every time your syringe needle has to penetrate something (rubber stoppers in vials, skin, etc) it dulls the tip.  Thus, maximum comfort is also achieved with fresh syringes.

This topic of “one or two syringes” can be argued, but if it’s your first time, play it safe and get off to a great start by using 2!

Pre-injection Aspiration 
Pre-injection aspiration is what you do after the needle has penetrated the muscle.  You must gently and slightly pull back on the needle’s plunger to see if you have hit a vein/artery.

Either of two things will happen upon aspiration:  A) bubbles/air and/or clear liquid will appear in the syringe (this is good), or B) blood will appear (bad).

If A) occurs, proceed with your injection. If B) occurs, then simply withdraw the needle, and re-pin a different location in that same muscle.  You do NOT want to inject your solution into a vein/artery!  This may result in very serious consequences.  Don’t worry, you can avoid this by simply aspirating slightly.  Have faith in yourself.

Injection Procedure
First, do not get all worked up over injecting IGF-1.  Easier said than done, I know.  But the reality is, the insulin syringes are extremely gentle.  Also, millions of people around the world, including women and children, use these syringes daily to treat Diabetes.  So you know it can’t be that bad (seriously)!  I highly recommend watching a couple videos on youtube regarding intramuscular (IM) injections to get a general idea of how they’re done if you’ve never witnessed them!

Back-Loading With Bacteriostatic Water (BW)
Back-loading is a process in which you dilute the IGF-1/AA solution that is in your syringe. The point is to dilute the acidity to a point that it will no longer cause tissue necrosis (death/damage) or pain upon injection.  It is recommended to dilute no less than 4:1 (4 parts BW to 1 part IGF-1/AA).

Example:  If you are injecting 40mcg bilat, IM, you will have two syringes each with 20mcg IGF-1.  Assume you want to draw 2 IU IGF-1. You will draw 2 IUs of the IGF-1/AA solution, then draw 2×4 = 8 IUs of BW (four times the amount of IGF-1/AA solution).  The total number of IUs in each syringe will be 2 + 8 = 10 IUs.  It will not hurt you if you decide to back-load with more BW.  It is a personal preference.

***Use my Excel-based “IGF-1” calculator to determine how many IUs you will need for a particular insulin syringe (1cc, 0.5cc, 0.3cc).

Recommended Best Injection Method:  Injecting bilaterally, post workout, intramuscularly (Bilat, PWO, IM)




Items you will need
1. Alcohol prep pads
2. 2 insulin syringes
3. Bacteriostatic water (BW)
4. Optional:  exam gloves
5. Optional:  IPA (to rub gloves with and to clean the surrounding area)

Injection Directions
1. Wash your hands thoroughly
2. Optional: put on exam gloves and rub with IPA until dry
3. Using an alcohol swab, clean the tops of both the IGF-1 vial and the BW vial.
4. Using a fresh alcohol swab, thoroughly clean the injection sites (let dry)
5. Fill each syringe with the appropriate amount of IGF-1/AA solution
a. Do NOT touch the needles to anything but sterile surfaces!
b. It is recommended that you clean/sanitize the area/surfaces you’re working in, in case you mindlessly touch a needle to a table (or other area).
6. Back-loading:  Draw up the necessary amount of BW into each syringe.
a. Tilt the needle up and down so the bubble(s) rise and fall, which mixes the solution slightly
7. With the needle pointing up, flick the syringe body to get the bubbles to rise to the needle
8. Slowly expel the air; be careful to not quirt liquid out as this wastes IGF-1
a. It takes >3mL of air to cause harm; small volumes of accidentally injected air will most likely be absorbed by muscle tissue
9. Insert syringe and aspirate by slightly pulling up on the plunger to see if you have hit a vessel. If you see blood, remove needle, and try again (no need to change syringes).  If you do NOT see blood, proceed to inject.
10. Perform “7.” thru “9” above on other side.
11. Discard sharps in appropriate container



Glossary

Acetic Acid (AA):  An acid that, when diluted to 0.6%, will act as a preservative for your IGF-1.  An off-the-shelf version of 5% AA is distilled white vinegar; your IGF-1 may be supplied in acetic acid (usually 0.6%)

Aspiration:  The technique of checking to see if your inserted needle is in a blood vessel.  It is performed by gently pulling up on the syringe plunger until you either see bubbles/air/clear liquid, or blood.  If you see blood, remove needle, and re-try the insertion.

Back-loading:  The process of diluting your IGF-1/AA with bacteriostatic water, prior to injection.  The purpose is to dilute the acidity of the AA so it doesn’t cause tissue damage and so it doesn’t cause injection burn/discomfort.
A. Draw desired amount of IGF-1/AA solution
B. Back-load with BW:  draw desired amount of BW

Bacteriostatic Water (BW)
:  This is water for injection (sterile) that has benzoyl alcohol (BA) added to it to ward of contamination.  You use BW to dilute your IGF-1/AA solution prior to injection (aka, “back-loading”).

Bilateral Injection (bilat):  An injection which involves the administration of IGF-1 in equal amounts to each side of the body.  If you are injecting 40mcg IGF-1 into the biceps bilaterally, you will be injecting 20mcg into each bicep (left & right side).

Distilled Water:  Has virtually all of its impurities removed through distillation. Distillation involves boiling the water and then condensing the steam into a clean cup, leaving nearly all of the solid contaminants behind. This is NOT sterile water.  It can be purchased in any grocery store in the “water” isle.

Endogenous:  Substances that originate from within an organism, tissue, or cell.  It is the opposite of exogenous

Exogenous:  Refers to an action or object coming from outside a system.  It is the opposite of endogenous.

IM: Intramuscular; typically refers to the type of injection where you inject a substance directly into muscle tissue

IGF-1 lr3:  A peptide that is responsible for new muscle tissue development; it is synthetic and has a much longer circulatory life than endogenous IGF-1

Lyophilized:  The form in which IGF-1 is typically supplied; this is a freeze-dried protein which is performed in a vacuum; appearance may range from a fine, loose white powder, to a white solid “paste”-type substance

PWO:  Post Work Out; refers to the time period when the administration of IGF-1 is thought to be the most effective (immediately PWO).

Reconstitution:  The addition of 0.6% acetic acid to lyophilized IGF-1r3 to get it into solution.  Typically one reconstitutes using 1mL or 2mL of acetic acid, yielding 1mg/mL or 2mg/mL of IGF-1/AA.

Sub-q:  Subcutaneous; typically refers to the type of injection where you inject a substance under the skin; this results in systemic distribution of substances

Author: PapaPumpSD


Reconstituting HGH

Reconstituting HGH the numbers breakdown

For an 10iu vial of HGH (human growth hormone), Jintropin and Generic Chinese

you add 1 ml (is=to 100iu’s on a slin pin) of bacteriostatic water or the sterile solution to your vial of HGH. . You will need to provide on some kits (chinese)  On an insulin needle 1iu of reconstituted gh is 10iu’s on the pin, so if your using 2iu’s of gh ed.. it would be 20iu’s on the insulin needle 3iu’s ed  it would be 30iu’s on the insulin needle 4iu’s ed  it would be 40iu’s on the insulin needle 5iu’s ed  it would be 50iu’s on the insulin needle 6iu’s ed  it would be 60iu’s on the insulin needle

 

For an 18iu vial of gh

you add 1 ml (1ml is equal to 100iu’s on a insulin needle) of bacteriostatic water or the solution they provide.  on a slin pin 1iu of reconstituted gh is 5.5iu’s on the pin  so if your doing  2iu’s of gh ed.. it would be 11iu’s on the insulin needle 3iu’s ed.. it would be 16.5iu’s on the slin pin 4iu’s ed.. it would be 22iu’s on the slin pin 5iu’s ed.. it would be 27.5iu’s on the slin pin 6iu’s ed.. it would be 33iu’s on the slin pin

21iu’s of active GH per vial

The fact is that we have 21iu’s of gh in each vial… Now we also have up to 1.6mls of bacteriostatic water to use.. It’s not necessary that we use it all..
We need to come up with a nice round number that would be easy to read and remember.  OK If we use 105iu’s of water to mix with the GH than we have a ratio of 1:5 1iu of Gh per 5 iu’s of water.
So if your doing  2iu’s of gh ed.. then thatwould be 10 on an insulin needle 3iu’s ed.. then thatw ould be 15 on a slin pin 4iu’s ed.. then that would be 20 on a slin pin 5iu’s ed.. then that would be 25 on a slin pin; 6iu’s ed.. then that would be 30 on a slin pin

 

and so on

You need to know how many iu’s your hgh is in powder form (before Reconstituting)

Complete step-by-step guide for peptide beginners

Peptide Guide

1 – You are on this site because you have heard of and want to become more familiar with Growth Hormone Releasing Peptide (GHRP) and/or Growth Hormone Releasing Hormone (GHRH). These 2 materials administered can give you an increased quality of life in ways of anti-aging, muscular hypertrophy, fat loss, injury repair, higher bone density, and better sleep.

2 – GHRP can be used on its own to increase our natural Growth Hormone (GH) pulse release from the Pituitary Gland in the brain. GHRP dosed in conjunction with GHRH will amplify our growth hormone release significantly to gain maximal benefit.

3 – There are various types of GHRH’s. The only GHRH to consider is tetra-substituted CJC-1295 / CJC-1295(without DAC) / modGRF(1-29). They are all the same thing but with a different name. They come in vials ranging in material weights measured in milligrams (mg) consisting of a solid freeze-dried (lyophilized) substance.

4 – There are various types of GHRP’s. GHRP-6, GHRP-2, Hexarelin, and Imaporelin. The differences between them are potency and side effects. GHRP-6 is very potent and makes you quite hungry. GHRP-2 is potent and can slightly affect your sleep somewhat. Hexarelin is very potent but you can desensitize from higher dosages. Imaporelin is potent with the minimalist side effects of all 4 GHRP’s.

5 – Peptides are dosed via a regular 1mL needle syringe typical to what a diabetic would use. It is administered Subcutaneously (SubQ) (just under the skin into the fat tissue), most usually around the abdomen region.

6 – The required amount (saturation dose) is 1mcg (microgram) per Kg (Kilogram) of bodyweight. The typical usage and for ease of measuring is 100mcg of modGRF(1-29) and/or 100mcg of your choice of GHRP. Lower dosages will simply result in less GH release due to a slightly weaker GH pulse and reduce any side effects you may have. A higher dose will have minimal benefit and is more a waste of money than anything else. But, in saying that, the more frequently dosed in any given day would result in more frequent pulses.

7 – Mixing (reconstitution) the lyophilized product in their vials with Bacteriostatic Water (BW) can take some getting used to. The idea is not to add too much dilution. Typical rule of thumb is to add 0.5mL of BW to 1mg of Peptide. So a 2mg vial should reconstitute with 1mL BW. 5mg with 2.5mL, 10mg with 5mL, etc. Squirt the BW along the inside wall of the vial in a smooth controlled manner being cautious not to agitate the mixture too much. It will dissolve itself and become clear. You can roll the vial gently between your fingers or hands but don’t shake it to dissolve. The reconstitute is ok to be drawn once fully dissolved.

8 – On a 1mL needle, there are either 50 tick marks from 0-100, skipping every odd number OR 100 international units (IU). A 100mcg dose is half way between the 2nd and 3rd tick mark, OR 5 IU’s (if you followed the above reconstitution). There are no half tick marks. It is OK to draw modGRF and GHRP into the one needle for a single shot. It is NOT OK to mix peptides in the same vial or syringe for storage.

9 – Reconstituted peptide should be stored in the refrigerator to prevent degradation. Left at room temperature, peptide will degrade within days but kept in the fridge will last months. You can pre-load syringes and store in freezer if you want but it is more of a hassle than being worth the effort.

10 – Doses can be taken throughout the day but at no less than 3 hour intervals between doses. 1 dose a day is typical for light injury repair, anti-aging effects, deeper sleep, and better quality of life. The most beneficial would be to dose immediately prior to going to bed for your daily sleep period. Sleep is the time when our pituitary is most active. 2 or 3 doses per day will give the added benefit of lean tissue build, and fat loss, considering your diet consists of good quality foods.

11 – Doses should be taken on empty stomach to benefit the most. This is usually 3 hours or more.

12 – Do not consume food for between 15-30 minutes after your dosage. Best time is around 20-25 minute mark. GH pulses should peak within about 10 minutes after dosage. Fats and Carbohydrates affect the pulse dramatically. Protein has no effect on pulse and you can have a pure protein source in your stomach at anytime if you so choose to.

13 – Dosage timing can be beneficial to your goals. For muscle growth, the 2nd most beneficial time to dose is post workout (PWO). Best time is pre-bed because sleep is when we recover and our cells repair and grow. Within 30 minutes should be fine but sooner the better. Remember to have your meal 20-25 minutes after dose.

14 – For fat loss, your supplemental dose is 1 hour pre-cardio exercise after a long fasting without food. Best time is after waking up and before breakfast. During cardio exercise, maintain a moderate intensity for between 30-60 minutes. 45 minutes is a good session. You do not want to go too hard or too long. A moderate pace will utilize Free Fatty Acids (FFA) at the highest rate for energy. Refrain from eating for approximately 2 hours after your exercise because this is the time the body is still burning fat as fuel. You must eat throughout the day to reduce the chance of muscle catabolism (breakdown).

15 – These Peptides can be used on a daily basis for the rest of your life without any harm. Enjoy!!!

Written and Thanks goes to Aussie