Melanotan II erections
a study done on it
Synthetic Melanotan II peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study.
PURPOSE Of the Melanotan II study :
We evaluated the erotogenic properties of a new cyclic alpha-melanocyte-stimulating hormone analogue, Melanotan-II, to treat men with psychogenic erectile dysfunction.
MATERIALS AND METHODS:
Ten men with erectile dysfunction of no known organic cause were entered in a double-blind, placebo controlled crossover study in which the erotogenic properties of Melanotan-II and a vehicle placebo were compared using real-time RigiScan monitoring. The presence, duration and rigidity of erections were recorded during a 6-hour period.
In 8 of 10 men treated with Melanotan-II clinically apparent erections developed. Mean duration of tip rigidity greater than 80% was 38.0 minutes with Melanotan-II and 3.0 with placebo (p=0.0045). Transient side effects of nausea, stretching and yawning, and decreased appetite were reported more frequently after injections of Melanotan-II than placebo but none required treatment.
Findings of the Melanotan II study :
Melanotan-II is a potent initiator of erections in men with psychogenic erectile dysfunction and has manageable side effects at a dose of 0.025 mg./kg.