Cyclofenil (same Chemical Name)

CYCLOFENIL (SAME CHEMICAL NAME)

Reported Characteristics

• Active Life: 8-12 hours
• Drug Class: Synthetic estrogen/gonadotropin stimulator/anti-estrogen (Oral)
• Average Reported Dosage: Men-400-600mg daily
• Acne: Rare/light
• Water Retention: Rare
• High Blood Pressure: Rare
• Strong gonadotropin stimulator/anti-estrogen
• Aromatization: None
• Liver Toxic: None noted

Cyclofenil administration is quite similar to using HCG and CLOMID together. It is an anti-estrogen and a gonadotropin/testosterone stimulator. It does so by occupying estrogen receptors (antagonist) with a much weaker estrogenic compound and by shutting down the negative feed-back within the hypothalamus-pituitary-testes-axis (HPTA). The male body actually can produce much more testosterone than it does. Simply said, it sees no reason to do so. When the hypothalamus senses adequate testosterone/estrogen levels, either naturally (endogenous) or unnaturally (exogenous) provided, it shuts off gonadotropin release from the pituitary/hypothalamus. Thus, leydig cells in the testes do not receive the signal to produce more testosterone. Cyclofenil interferes with this negative feed-back/shut down production signal. This means that the hypothalamus - pituitary-testes-axis runs wide open to some extent, and more testosterone is produced. After about 5-6 weeks the hypothalamus figures this out and really shuts down the goodies production.
Though some strength and mass resulted with Cyclofenil use, it was not noted as a great growth drug. Some "natural" (okay) bodybuilders have used it with some results as have older individuals. However, the chemically assisted lads have used it to kick start natural testosterone production and even as a "during cycle anti-estrogen" very successfully. Normally 200 mg was taken 2-3 times daily for 4-6 weeks, either starting the last 3 weeks prior to the end of an AAS cycle or directly following a cycle. The prior method being reported as more effective since about a week is necessary for Cyclofenil to become effective and provide results. Side effects commonly reported have been; light acne, elevated sex-drive (that is a side effect?), and hot flashes.
TRADE NAMES

• FERTODUR 200MG TABS
• FERTODUR 200MG TABS
• NEOCLYN 200MG TABS
• ONDOGYNE 400MG TABS
• REHIBIN 100MG TABS
• SEXOVID 100MG TABS

*A note of interest; I have known several so-called natural bodybuilders who have utilized cyclofenil with a prohormone protocols in the United States with surprising results. This was effective for many reasons. Lower estrogen activity means a harder appearance. Testosterone both endogenous and exogenous combine resulted in significant total testosterone levels as well as a higher free testosterone level due to prohormones ability to uncouple testosterone from SHGB to some extent. The usual cycle consisted of 6 weeks of prohormones with 4 weeks of cyclofenil beginning week #5 of the prohormone cycle. Doing so extended the cycle 2 weeks and assured no post-cycle HPTA suppression to deal with for most athletes. Some athletes reported week #6-8 produced good secondary growth. This may have been due to an up- regulation of LH, FSH, and the conversion enzymes responsible for prohormones becoming testosterone in blood as well as decreased activity of estrogen. My concern would be the rush of estrogen post-cycle since cyclofenil only blocks estrogen receptors instead of suppressing estrogen production. In that example, for me personally, Arimidex would have been a wiser choice beginning week #5 also.