Archive for July 2014

GHRP-2

GHRP-2

CAS:
Formula: C45H55N9O6
Molecular weight: 817.9
Peptide purity: > 98.0%
Appearance: White powder
Related substance: Total Impurities(%) = 2.0%
Acetate content: = 15.0%
Bacterial Endotoxins: =5 IU/mg
Chain:D-Ala-D-ß-Nal-Ala-Trp-D-Phe-Lys-NH2

Uses

Improve sex drive and desire by stimulation of hypothalamus
Reduces belly fat through lipolysis
Increases energy and vitality
Improves skin elasticity, ridding wrinkles
Increases endurance
Accelerates healing from wounds or surgery
Strengthens the heart
Enhances the immune system
Increases IGF-1 production, by as much as 50% in first week
Improves sleep quality
Increases calcium retention, strengthens and increases the mineralization of bone, bone density
Increases protein synthesis,
Improves eyesight and vision
Reduces liver uptake of glucose, an effect that opposes that of insulin
Promotes liver glucogenesis
Contributes to maintenance and function of pancreatic islets

GHRP2 growth hormone releasing peptide therapy is considered one of a few medical means of reversing the effects of aging in adults deficient in growth hormone. This is because of the benefits resulting from the increased stimulation and secretion of human growth hormone by the pituitary gland hypothalamus,axis HPA.

GHRP-2 also known as KP 102 is a commercially synthesized, growth hormone releasing hexapeptide. It is a super-analog of the GHRP-6 which is capable of potent stimulatory effect on growth hormone (GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol).

Growth Hormone Releasing Peptide 2(GHRP-2) substantially stimulates the pituitary gland’s increased natural production of the body’s own endogenous human growth hormone (hgH). This therapy consists of daily periodic sub-lingual dosing. Growth Hormone releasing peptide 2, GHRP-2 has shown on it’s own to robustly increase IGF-1 levels, and even greater results occurred when used with Growth Hormone Releasing Hormone (GHRH) to which also stimulates the pituitary gland to produce increased natural secretion of human growth hormone. This also boosts the hypothalamus function as well.

GHRP-2 is a true hgH secretagogue. It stimulates the body’s own secretion of hgH as explained herein. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat). GHRP2 has demonstrated that it is very effective at stimulating GH production in research test subjects. It has a short half life with peak concentrations occurring around 15 minutes and not longer than 60 minutes after administration.

Growth hormone releasing peptide is a commercially synthesized, non-natural super-analog of the GHRP-6 which is capable of potent stimulatory effect on growth hormone (GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol (Arvat et al. 1997). It is also a synthetic agonist of ghreline that is binding with the growth hormone (GH) secretagogue receptor. GHRP-2 has been shown to affect and induce growth hormone secretion. The response of natural physiologic system includes increase in levels of calcium ion influx alongside with increased release of growth hormones in response to this peptide (Wu et al. 1994). Its chemical structure and other chemical properties are described below:

Furthermore, dose-dependent investigations have proven that this analog is similar in terms of potency with GRF and was even tenfold more potent than earlier generations of GH-releasing secretors such as GHRP-6 and GHRP-1 (Wu et al. 1994). Because of such effects, this hormone has been used for the treatment of different monkey deficiencies and catabolic states. Studies of Laferre et al. (2005) have shown that GHRP-2 acts like ghrelin which induces food intake in monkeys and also stimulates GH secretion. This has been demonstrated when GH levels rose significantly during GHRP-2 infusion (AUC 5550 ± 1090 µg/L/240 min vs. 412 ± 161 µg/L/240 min, p = 0.003). Also, GHRP-2 has shown to be inducing secretion of cAMP in cells in a manner similar to that of GRF. GHRP-2 supplication has also acted as an anti-inflammatory effect in arthritic rats and seems to be mediated by ghrelin receptors directly on immune cells (Granado et al. 2004). However, it is important to note that the level of results with the action of GHRP-2 differs accordingly with species specifically in the response of the pituitary somatotrophs probably because of differences in the subtypes of GHRP receptors (Wu et al. 1996). Its action however in the physiologic system is blocked by GRF receptor antagonist which acts through a different receptor to that employed by earlier GHRPs.

Arnold Schwarzenegger’s Old School Bodybuilding Workout

Arnold Schwarzenegger’s Old School Bodybuilding Workout

Arnold is probably the most famous bodybuilder of all time, he won Mr. Olympia
seven times (1970-1975, 1980) and brought bodybuilding into the national spotlight
in the movie “Pumpin Iron”.

Arnold’s Top Form Measurements

Arms 22 inches
Chest 57 inches
Waist 34 inches
Thighes 28.5 inches
Calves 20 inches
Weight 235 pounds
Height 6’2″

Arnold was from the old “No Pain No Gain” school of bodybuilding and his
routines consisted of high sets and reps, mostly not to failure. He trained
each muscle group three times each week (except calves, forearms & abs
which he trained every day), using a six day split routine.

There was very little rest between sets, and he usually increased weight each
and every set. Although he experimented with high reps at times, he usually
preferred a rep range of about 6 to 10.

The following is a typical Arnold routine, but be aware that Arnold’s routine
changed constantly. At times he trained twice a day, while at other times
once a day was enough. There were periods when he did lots supersets
and giant sets. Arnold tried every thing, and picked what worked best for
him at that particular time. By mixing things up he challenged his strength
and endurance and the training variety helped keep him fresh and motivated!

Remember this is a very advanced bodybuilding routine and should not be used
by beginners or intermediates, and even advanced bodybuilder’s should only
take what they think will work best for them and adapt it to their own
bodybuilding philosophy.

Arnold’s Workout Routine

Mon, Wed, Fri

Chest:
Bench press 5 x 6-10
Flat bench flyes 5 x 6-10
Incline bench press 6 x 6-10
Cable crossovers 6 x 10-12
Dips (body weight) 5 x failure
Dumbell pullovers 5 x 10-12.

Back:
Wide-grip chins (to front) 6 x failure
T-bar rows 5 x 6-10
Seated pulley rows 6 x 6-10
One-arm dumbell rows 5 x 6-10
Straight-leg deadlifts 6 x 15

Legs:
Squats 6 x 8-12
Leg press 6 x 8-12
Leg extensions 6 x 12-15
Leg curls 6 x 10-12
Barbell lunges 5 x 15

Calves:
Standing calf raises 10 x 10
Seated calf raises 8 x 15
Oneplegged calf raises (holding dumbells) 6×12

Forearms:
Wrist curls (forearms on knees) – 4 sets, 10 reps
Reverse barbell curls – 4 sets, 8 reps
Wright roller machine – to failure

Abs:
1/2 hour of a variety of nonspecific abdominal exercises, done virtually nonstop.

Tues, Thurs, Sat

Biceps:
Barbell curls 6 x 6-10
Seated dumbell curls 6 x 6-10
Dumbell concentration curls 6 x 6-10

Triceps:
Close-grip bench presses 6 x 6-10
Pushdowns 6 x 6-10
French press (barbell) 6 x 6-10
One-arm triceps extensions (dumbell) 6 x 6-10

Shoulders:
Seated barbell presses 6 x 6-10
Lateral raises (standing) 6 x 6-10
Rear-delt lateral raises 5 x 6-10
Cable lateral raises 5 x 10-12

Calves , Forearms & Abs:
Same as Monday, Wednesday, Friday workout

Pumping Iron (25th Anniversary Special Edition)

Own this classic bodybuilding movie on DVD!
This movie is a must have for any bodybuilding fan!
We only have limited number of videos available.